Trevor a Graham

Latest

• Negative Selection Maintains Grossly Altered but Broadly Stable Karyotypes in Metastatic Colorectal Cancer
• Quantitative measurement of phenotype dynamics during cancer drug resistance evolution using genetic barcoding
• Contribution of pks+ E. coli mutations to colorectal carcinogenesis
• Stabilising selection causes grossly altered but stable karyotypes in metastatic colorectal cancer
• Detecting repeated cancer evolution from multi-region tumor sequencing data
• Quantification of subclonal selection in cancer from bulk sequencing data
• Identification of neutral tumor evolution across cancer types
• A Big Bang model of human colorectal tumor growth