Andrea Sottoriva

Latest

• Genomic landscape of diffuse glioma revealed by whole genome sequencing
• MIDAA: deep archetypal analysis for interpretable multi-omic data integration based on biological principles
• Quantitative measurement of phenotype dynamics during cancer drug resistance evolution using genetic barcoding
• Single cell multi-omic whole genome sequencing and chromatin accessibility profiling reveals genome-epigenome coevolution in colorectal cancer
• Contribution of pks+ E. coli mutations to colorectal carcinogenesis
• Quantification of spatial subclonal interactions enhancing the invasive phenotype of pediatric glioma
• Stabilising selection causes grossly altered but stable karyotypes in metastatic colorectal cancer
• Detecting repeated cancer evolution from multi-region tumor sequencing data
• Quantification of subclonal selection in cancer from bulk sequencing data
• Identification of neutral tumor evolution across cancer types
• A Big Bang model of human colorectal tumor growth
• Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics