Inmaculada Spiteri

Latest

• Contribution of pks+ E. coli mutations to colorectal carcinogenesis
• Phenotypic plasticity and genetic control in colorectal cancer evolution
• The co-evolution of the genome and epigenome in colorectal cancer
• Exploiting evolutionary steering to induce collateral drug sensitivity in cancer
• Stabilising selection causes grossly altered but stable karyotypes in metastatic colorectal cancer
• Longitudinal liquid biopsy and mathematical modeling of clonal evolution forecast time to treatment failure in the PROSPECT-C phase II colorectal cancer clinical trial
• Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics