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Circulating tumor DNA dynamics and clinical outcome in metastatic colorectal cancer patients undergoing front-line chemotherapy
Michele Ghidini
,
Jens Claus Hahne
,
Chiara Senti
,
Timon Heide
,
Paula Z Proszek
,
Ridwan Shaikh
,
Paul Carter
,
Mike Hubank
,
Francesco Trevisani
,
Ornella Garrone
,
Others
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DOI
Computational pathology applied to clinical colorectal cancer cohorts identifies immune and endothelial cell spatial patterns predictive of outcome
Nicholas Trahearn
,
Chirine Sakr
,
Abhirup Banerjee
,
Seung Hyun Lee
,
Ann-Marie Baker
,
Hemant M Kocher
,
Valentina Angerilli
,
Federica Morano
,
Francesca Bergamo
,
Giulia Maddalena
,
Others
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DOI
Epigenetic Heritability of Cell Plasticity Drives Cancer Drug Resistance through a One-to-Many Genotype-to-Phenotype Paradigm
Erica a Oliveira
,
Salvatore Milite
,
Javier Fernandez-Mateos
,
George D Cresswell
,
Erika Yara-Romero
,
Georgios Vlachogiannis
,
Bingjie Chen
,
Chela T James
,
Lucrezia Patruno
,
Gianluca Ascolani
,
Others
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DOI
Genomic landscape of diffuse glioma revealed by whole genome sequencing
Ben Kinnersley
,
Josephine Jung
,
Alex J Cornish
,
Daniel Chubb
,
Ross Laxton
,
Anna Frangou
,
Andreas J Gruber
,
Amit Sud
,
Giulio Caravagna
,
Andrea Sottoriva
,
Others
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DOI
Heterogeneity and evolution of DNA mutation rates in microsatellite stable colorectal cancer
Elena Grassi
,
Valentina Vurchio
,
George D Cresswell
,
Irene Catalano
,
Barbara Lupo
,
Francesco Sassi
,
Francesco Galimi
,
Sofia Borgato
,
Martina Ferri
,
Marco Viviani
,
Others
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DOI
MIDAA: deep archetypal analysis for interpretable multi-omic data integration based on biological principles
Salvatore Milite
,
Giulio Caravagna
,
Andrea Sottoriva
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DOI
MYC ecDNA promotes intratumour heterogeneity and plasticity in PDAC
Elena Fiorini
,
Antonia Malinova
,
Daniel Schreyer
,
Davide Pasini
,
Michele Bevere
,
Giorgia Alessio
,
Diego Rosa
,
Sabrina D’Agosto
,
Luca Azzolin
,
Salvatore Milite
,
Others
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DOI
Quantitative measurement of phenotype dynamics during cancer drug resistance evolution using genetic barcoding
Frederick JH Whiting
,
Maximilian Mossner
,
Calum Gabbutt
,
Christopher Kimberley
,
Chris P Barnes
,
Ann-Marie Baker
,
Erika Yara
,
Andrea Sottoriva
,
Richard a Nichols
,
Trevor a Graham
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DOI
Single cell multi-omic whole genome sequencing and chromatin accessibility profiling reveals genome-epigenome coevolution in colorectal cancer
Maximilian Mossner
,
Chloé Colson
,
Qingli Guo
,
Freddie Whiting
,
Heather Grant
,
Amanda Stafford
,
Peter Kyle
,
Daniella Donato-Brown
,
Jamie Murphy
,
Andrea Sottoriva
,
Others
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DOI
Stratified Medicine Pediatrics: Cell-Free DNA and Serial Tumor Sequencing Identifies Subtype-Specific Cancer Evolution and Epigenetic States
Sally L George
,
Claire Lynn
,
Reda Stankunaite
,
Debbie Hughes
,
Carolin M Sauer
,
Jane Chalker
,
Saira Waqar Ahmed
,
Minou Oostveen
,
Paula Z Proszek
,
Lina Yuan
,
Others
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DOI
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